Development of Biologics:
Our Experience – Your Track to Success

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Meso Scale Discovery (MSD)
The Multiplexing platform

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Gyrolab
The nanoliter-scale immunoassay platform

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Advanced detection modes
Alpha Technology - TR-FRET - TRF

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BD FACSLyric and assay portability:
the key to efficient method transfer and high data reproducibility

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Our Quality Standards

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In touch with science – to success in market!

IBR Inc. Services

Pharmacokinetics

Pharmacokinetics (PK) studies are a key aspect of the drug development process. Data on drug Absorption Distribution, Metabolization and Elimination (ADME) are important elements for evaluation of efficacy and safety. Furthermore, PK-data provide essential guidance for identifying the appropriate dosing regimen.

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Immunoassay platforms

Meso Scale

IBR Inc. offers the MSD ECL immunoassay platform. The SECTOR S 600 instrument is a powerful tool whenever an assay demands multiplexing with high sensitivity, even in complex matrices, such as serum or plasma.

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Advanced detection modes

Alpha – TR-FRET – TRF

Complementing the classical detection modes, the advanced Time-Resolved Fluorescence (TRF) and proximity detection modes like TR-FRET and Alpha widen up the ways to detect biomolecular interactions and functions.

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HiTech platforms

BD FACSLyric

Our BD FACSLyric has been designed to achieve a high level of standardization. The assay settings can be easily transferred to another cytometer, thereby substantially reducing instrument to instrument variation.

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Quality at IBR Inc.

Our standards

The IBR Inc. laboratories are GLP compliant since 2001 and directed by our in-house Quality Assurance Manager. The quality standard of Good Clinical Practice has been introduced at IBR Inc. in 2012.

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Services

Cell-based assays

IBR Inc. has a longstanding experience in cell-based assays including primary cells, transformed cell lines, reporter-gene as well as 3D cell systems.

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Our focus

IBR Inc., Institute for Biopharmaceutical Research is a Swiss GxP-compliant contract research organization founded in 1998. We are a first-in-class site in the field of bioanalytical services for new biological entities (NBE), like therapeutic antibodies, as well as new chemical entities (NCE), antibody-drug conjugates and vaccines. We are covering the bioanalytical needs from discovery over pre-clinical to clinical development and market.

We are experienced in driving studies on cytokines, chemokines and other biomarkers, drug/target binding and immunogenicity. Furthermore, we perform cell-based assays with a broad variety of readouts. Our team has vast experience with primary cells, transformed cell lines, transfected cells, reporter-gene cell systems and 3D cell-based assays.

IBR Inc. moves on with rapid and constantly growing advances in technology and offers advanced platforms including Alpha Technology, Time Resolved Fluorescence (TRF), MSD® ECL, Gyrolab™, state-of-the-art Flow Cytometry / Cytometric Bead Array and real time PCR, beside a broad variety of classical techniques.

With IBR Inc. your studies are supported from assay development to assay validation and sample measurement. We have capability to perform studies in compliance with regulatory guidelines for GLP, GMP and GCP quality standards, following the principles of ICH Q2 (R1), USP 1032, 1033, 1034 and the EU GMP requirements. Our study reports are compliant with eCTD requirements.