Bioanalytics

Early research in preclinical R&D includes characterisation of Active Pharmaceutical Ingredients (APIs) using a broad range of bioanalytical techniques.  Development and validation of specific assays is inevitable in most  preclinical R&D projects. IBR Inc. provides straight forward strategies to apply step by step the most appropriate techniques designed also to efficiently meet tough time limits.

Techniques

Due to the diverse nature of APIs, a wide variety of highly specific techniques are employed. Techniques established at IBR Inc. are:

  • Cell based assays, more...
  • Reporter gene assays, more...
  • Ligand binding assays
  • ELISA, more...
  • ELISpot, more...
  • AlphaLISA, the non-wash alternative to ELISA
  • Cell proliferation assays (MTT, WST-1)
  • FACS endpoints
  • FACS cell surface and intracellular antigens, cytotoxicity
  • Multiplexed cytokine determination, more...

Molecular biology

IBR Inc. provides development and validation of molecular analytical methods. These methods may be applied for the determination of genetic stability for recombinant cell lines and for the characterization of plasmid products. More...

Biochemistry

IBR Inc. applies various analyses in the field of biochemistry. Based on gel electrophoresis, individual purity and identity testing procedures of DNA/RNA or protein products are offered. Endotoxin content testing of recombinant products is also available. GLP validations of these customer specific methods are provided as a supplementary service. More...